Abstract: Based on the genetic engineering pharmaceutics module of the biotechnological pharmaceutics course, by expanding teaching ideas and reasonably organizing teaching contents, a stepwise guiding teaching strategy was developed. In the foundation stage, bilingual and interactive teaching based on teaching the basic technology and theory of genetic engineering pharmaceutics was carried out to establish a consolidated knowledge background and further cultivate students’ learning consciousness. In the advanced stage, the production design course was introduced to connect the theory and practice to cultivate students’ pharmaceutical process innovation ability. In the ascending stage, the genetic engineering pharmaceutics innovation experiments were set up to cultivate students’ innovation abilities in drug research and development. Results showed that stepwise guiding teaching was of good effect through the bilingual teaching and research progress teaching of principles of genetic engineering pharmaceutics, combined with the production design course and biotech drug research practice.

Key words: biotechnological pharmaceutics, genetic engineering pharmaceutics, stepwise guiding teaching, production design, innovative ability